Introduction

Query

References

About

Introduction

ProTarget offers a novel method for the prediction of new structural superfamilies.

Given a new sequence, it is inserted into a hierarchical clustering of the protein space, and its location relative to known (solved) structures is computed.

Based on the distance in the hierarchy between the new sequence and solved structures, a prediction is made, along with a score indicating the confidence associated with this prediction.

The method underlying ProTarget is described in Bioinformatics 2005:

Predicting fold novelty based on ProtoNet hierarchical classification [PDF, 248KB]
Ilona Kifer, Ori Sasson and Michal Linial

Citation: Groups using results derived from this webserver for publication are asked to cite Nov 11;
Kifer I, Sasson O, Linial M.(2004) Predicting fold novelty based on ProtoNet hierarchical classification. PMID: 15539447